EMS HELI HAS CARGO DOORS DEPART THE ACFT AT CRUISE.

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STAT EMS WAS DISPATCHED TO CITY; STATE A; FOR A MEDICAL TRANSPORT. DEST HOSPITAL IN CITY; STATE B. EMS HELI LIFTED OFF XYZ AND ARRIVED AT HOSPITAL A. THE CREW CONFIGN CONSISTED OF THE PLT; 2 CREW MEMBERS AND A PATIENT. THE PATIENT WAS LOADED ONTO THE ACFT. THE PLT CONDUCTED A WALK-AROUND INSPECTION BEFORE BOARDING THE ACFT AND THE CREW MEMBERS LOADED THE MEDICAL BAGS IN THE CARGO/STORAGE AREA. THE CREW MEMBERS SECURED THE PATIENT AND THE CARGO AREA AND CALLED CLR TO THE PLT. AFTER WE LIFTED WE HEARD A BANG THAT SOUNDED ABNORMAL. I ADVISED APCH THAT I WAS DIVERTING TO THE XYZ ARPT. THEY TERMINATED RADAR SVC AND I CONTACTED XYZ TWR. I LANDED WITHOUT INCIDENT AND INSPECTED THE ACFT FOR DAMAGE. UPON INSPECTION IT WAS NOTED THAT BOTH CARGO DOORS HAD SEPARATED FROM THE ACFT IN FLT. IT WAS DETERMINED THROUGH VISUAL INSPECTION AND REF TO THE ACFT MEL AND FLT LIMITATIONS THAT THE HELI WAS SAFE FOR THE CONTINUATION OF FLT AT A VNE OF 70 KTS. FLT WAS TERMINATED AT XXX WITHOUT FURTHER INCIDENT AT XX02. I BELIEVE THE CAUSE OF THE PROB TO HAVE BEEN AN OVERLOADING OF THE CARGO AREAS. I DID NOT GET AN ILLUMINATED DOOR LIGHT INDICATING THE DOOR ALTAR ON THE CAUTION ADVISORY PANEL. TO PREVENT THIS FROM HAPPENING AGAIN; THE CARGO DOORS WILL BE LOCKED WITH A KEY FOR EVERY FLT AND A COMPANY MECH WILL TRAIN AND DEMONSTRATE THE PROC FOR SECURING THE CARGO DOORS TO ALL FLC MEMBERS.