REJECTED TKOF PERFORMED BY PIC WHEN CREW REALIZES FO'S SLIDING WINDOW IS UNLOCKED DURING DEP FROM AFW; TX.

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OUR PUSHBACK; ENG STARTS AND TAXI TO RWY 34R WERE UNEVENTFUL. WE HELD SHORT OF THE RWY ON TXWY A AND COMPLETED THE 'BEFORE TKOF' CHKLIST. WHEN CLRED FOR TKOF; I TAXIED ONTO THE RWY; LINED THE ACFT ON CTRLINE; AND GAVE THE ACFT TO THE FO PF. WIND WAS 350 DEGS AT 20 KTS GUSTING TO 27 KTS. THE FO CALLED 'SET MAX PWR;' WHICH I DID. AS WE ACCELERATED DOWN THE RWY; I HEARD AN INCREASING LOUD ROARING NOISE COMING FROM THE R SIDE OF THE COCKPIT. PASSING 100 KTS; I LOOKED OVER TO THE FO'S SIDE AND SAW HIS CANOPY LOCK HANDLE IN THE STRAIGHT-UP POS; THE UNLOCKED POS. I CALLED OUT TO THE FO THAT HIS CANOPY WAS UNLOCKED. HE PUT HIS R HAND ON THE HANDLE AND TRIED TO PUSH IT FORWARD TO LOCK IT; WITHOUT SUCCESS. I COULD NOT TELL IF THE CANOPY WAS OPEN OR NOT; BUT THE WIND NOISE WAS BECOMING EXTREMELY LOUD. I NOTED OUR AIRSPD AT 120 KTS; CALLED OUT 'I HAVE THE ACFT; REJECT;' PULLED THROTTLES TO IDLE; WENT TO REVERSE THRUST AND COMMENCED BRAKING V1 SPD WAS 141 KTS. THE ACFT SLOWED EASILY TO TAXI SPD DUE TO THE HIGH HEADWIND AND UPSLOPE OF THE RWY. I COULD HAVE EASILY TURNED OFF RWY AT TXWY G BUT ELECTED TO CONTINUE TO TXWY H. I STOPPED ACFT ON TXWY A AFTER TURNING OFF AT TXWY H. TWR NOTED NO SMOKE FROM BRAKES/TIRES. COMPANY MAINT ARRIVED AND CHKED BRAKES AND TIRES. WE DETERMINED FROM THE REJECT CHARTS THAT 135 MINS WOULD BE REQUIRED FOR BRAKE COOLING. THE SO (FE) SAID HE SAW 130-135 KTS BEFORE ACFT STARTED TO SLOW UP; BUT I NEVER SAW A SPD ABOVE 120 KTS. THE CANOPY LOCK HANDLES ARE CHKED 'CLOSED AND LOCKED' IN THE 'AFTER ENG START' CHKLIST AFTER ENGS ARE STARTED. SUPPLEMENTAL INFO FROM ACN 542167: FO'S WINDOW LOCK HANDLE WAS FOUND TO BE OUT OF THE FULL FORWARD LOCKED/LATCHED POS. RED STRIPES WERE ALIGNED AND THERE WAS NO NOTABLE OPENING IN THE FO'S WINDOW.