PLT OF C208; UNFAMILIAR WITH EWR; GETS DISORIENTED ON NIGHTTIME ARR AND LANDS ON TXWY AFTER FAILING TO EXECUTE VFR APCH TO RWY 11.

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PART 135 CARGO FLT FROM ZZZ TO EWR. ATIS RPTED RWY 4R AS LNDG RWY. APCH ASKED IF I COULD ACCEPT RWY 11. THIS WOULD BE A XING TAILWIND BUT I ACCEPTED THE APCH TO RWY 11. I WAS VECTORED TO THE RWY 11 LOC; MAINTAIN 2000 FT UNTIL ESTABLISHED. I FAILED TO FACTOR IN APPROX 30+ KT TAILWIND AT 2000 FT. IT IS OFTEN DIFFICULT TO SPOT RWY 11 FROM A DISTANCE IF YOU ARE LOW; BECAUSE IT IS SOMEWHAT DOWN IN A HOLE SURROUNDED BY LIGHTS. SINCE VISIBILITY WAS UNLIMITED I EXPECTED TO SEE THE RWY. I DID NOT SEE IT; SO I CONTINUED AT APPROX 2000 FT DOWN TO 1500 FT. I REALIZED I WAS OVER THE APCH END OF THE RWY; HIGH AND FAST. I WAS GOING TO INITIATE A GAR WHEN TWR SAID RWY 22R WAS AVAILABLE. I ACCEPTED THAT CLRNC; MADE A TURN TO THE L AND THEN AROUND TO R TO LINE UP WITH RWY 22R. ACFT WERE STILL USING RWY 4R FOR LNDG AND I DID NOT WANT THE STRONG W WIND TO BLOW ME E INTO THEIR PATH. AT THIS POINT; I WAS OVER THE APCH END OF RWY 22R AND COULDN'T SEE THE RWY END LIGHTS. THERE ARE A NUMBER OF PARALLEL SURFACES AND LIGHTS. RWY 22L; TXWY P; RWY 22R; TXWYS R; B; D; TXWYS S; A; PA. I MISTOOK THE CTRLINE LIGHTS OF TXWYS R; B; D; FOR RWY 22R AND LANDED ON IT. I REALIZED THIS ON TOUCHDOWN; THE TXWY EDGE LIGHTS WERE NOT ON. THERE WERE NO ACFT ON OR NEAR THE TXWY. CONTRIBUTING FACTORS: OFTEN THE TWR LANDS OUR COMPANY ON RWY 11 TO KEEP US OUT OF THE FASTER JET TFC TO THE MAIN RWY. TFC PERMITTING; A CLRNC TO RWY 22 WILL BE GIVEN TO SAVE A LONG TAXI TO THE FREIGHT FACILITIES. OUR OTHER PLTS OPERATE INTO EWR EVERY NIGHT AND ARE FAMILIAR WITH THE ARPT AND PROCS. I AM A 'FLOATER' AND OPERATE INTO SEVERAL ARPTS. I HAD DONE THIS SWITCH FOR RWY 11 TO RWY 22 BUT IN THE DAY TIME; NEVER BEFORE AT NIGHT. I WAS TIRED; HAD LEGAL REST TIME; BUT WAS UNABLE TO SLEEP. I SHOULD HAVE GONE AROUND TO RWY 11 AGAIN; OR ASKED FOR RWY 4R; OR PROCEEDED FURTHER TO THE NE FOR A LONGER APCH INTO RWY 22R WITH RWY END LIGHTS; TOUCHDOWN LIGHTS; ETC; IN VIEW SO THERE WOULD BE NO CONFUSION AS TO WHAT LIGHTS WERE WHAT.