CRJ 700 First Officer reported observing a Left Bleed Duct warning message during cruise resulting in a cabin depressurization. The crew descended immediately and landed at the destination airport.

Narrative

In cruise in IMC in icing with wing and cowl anti ice on we got a DUCT MON FAULT" status message. I looked through the QRH to see the meaning behind it. Once finished that we immediately got a "L BLEED DUCT" caution message and immediately after turned into a warning message. The Captain told me to run the QRC for it which there was no immediate action items for it. So then the Captain gave me the controls so he can run the QRH. I saw on the Environmental Control System (ECS) page that the left duct was red and all bleed valves closed. During this procedure I looked at the cabin pressure and saw it rising. I told the Captain "the cabin pressure is rising" which I also noted my ears starting to pop a lot. The Captain and I decided to do an emergency descent down to avoid totally losing the cabin. We donned our masks made sure the jump seater was going to put his on too. [Requested priority handling] down to 11000 feet. Down at a safe altitude we took off our oxygen masks and completed the remaining emergency descent checklist. The Captain transferred the controls back to me so he can focus on running checklists. We then decided to keep going to ZZZ since ZZZ1 was directly behind us equal distance. ZZZ2 was closest to us however the hurricane was coming through and we did know if it already hit them. ZZZ also being a maintenance base. At 11000 feet we got the "CABIN ALT" warning message since the cabin was at 10000 feet so we descended down to 8000. We continued running the "L BLEED DUCT" warning checklist which had a lot of overlapping stuff from the previous checklists. Transferred the controls back to the Captain so we can start running other items like getting updated weather and landing data and sending messages to Dispatch. During the cruise down at 8000 ft we kept getting "AUTOPILOT IS LWD" caution message. Other status messages were displayed like "stab ch 2 inop" and "left fadec fault 2". Landed in ZZZ where we had medics waiting for us at the gate. Operations were not ready for us when we landed so we had to call multiple times for rampers and gate agent. They did not know we were emergency either. While the passengers were in the jet bridge I told them that if anyone feels faint or does not feel right we have medical personnel waiting inside the terminal. The last thing I did was do my post flight walk around and went back inside the flight deck to help the Captain in any way.Cause: Duct mon fault followed by left bleed duct overheat."