CRJ-200 air carrier flight crew reported near stall event on approach.

Narrative

During the flight to the destination; our anticipated landing weight was a threat. In an attempt to burn more fuel to arrive at/or beneath max landing weight; we used high drag configurations for most of the arrival and approach. On the ILS approach at flaps 30; at 170 knots; with spoilers deployed; we experienced significant wind shear with a loss of almost 30 knots. Although my first officer was making appropriate and timely corrections with the thrust; the aircraft entered a low energy state; the stick shaker activated; and the autopilot disconnected. The first officer (PF) assumed manual control of the aircraft. I quickly stowed the spoilers. The aircraft did not enter an upset attitude. The remainder of the approach was uneventful; although we executed a missed approach after not being able to burn off the fuel necessary to stay within weight limitations.The subsequent approach and landing was uneventful.The primary cause of this event was the adverse weather. There were scattered thunderstorms with significant virga in the area. Multiple aircraft on frequency were reporting moderate or greater turbulence and wind shear down the approach corridor after we had experienced it ourselves.This event could be avoided by identifying the increased threat of a slow speed event when using spoilers right down to the limitation without consideration for environmental factors. We were at 170 knots while our weight/speed card produced a straight in speed of 149. Meaning the limitation allowed us to use the spoilers down to 169 knots. Under nicer conditions; this wouldn't have produced a low speed event. But combined with the unanticipated wind shear; it did.