A B727 FO ADMITTED THAT HE; THE FE; AND THE CAPT WERE DISTRACTED BY A FLT ATTENDANT ISSUE; CAUSING A TRACK DEV IN BOS AIRSPACE.

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UNTIL THE OCCURRENCE; CAPT WAS THE PF AND THE COPLT WAS THE PNF. FLT ATTENDANT ENTERED THE COCKPIT AND STATED SHE HAD SPILLED SOME COFFEE ON A PAX AND WOULD BE FILLING OUT AN INCIDENT RPT. AT THIS POINT; WE HAD PASSED THE RKA VOR ON THE ARR INTO BDL AND THE COPLT HAD SET UP THE NEXT INTXN ON VOR #2. CAPT TOLD COPLT TO FLY THE ACFT AND EVERYTHING WAS SET UP. COPLT ASSUMED THE PF DUTIES AND FLEW OFF THE CAPT'S HSI. CAPT HAD NOT SET UP THE OUTBOUND COURSE CORRECTLY AND THE COPLT DID NOT CATCH THE ERROR. ACFT PROCEEDED OFF COURSE. CAPT'S ATTN WAS FOCUSED ON THE FLT ATTENDANT AND HER INCIDENT RPT. ZBW EVENTUALLY QUESTIONED US AND WE DISCOVERED AND CORRECTED OUR ERROR. CONTRIBUTING FACTORS INCLUDE: SHORT LAYOVER THE PREVIOUS EVENING; LONG SIT AT THE ARPT THE DAY OF THE INCIDENT; CAPT'S FAILURE TO SET UP THE APPROPRIATE COURSE; FO'S FAILURE TO CATCH THE INCORRECT COURSE; THE FE'S FAILURE TO CATCH THE MISTAKE; AND THE CAPT'S ATTN BEING DIVERTED FROM THE ACFT. FATIGUE AND A LACK OF ADEQUATE REST WERE THE PRIMARY FACTORS CONTRIBUTING TO THIS OCCURRENCE.