On February 2, 2012, about 1442 Alaska standard time, Volga-Dnepr Airlines flight VDA 4410, an Antonov AN-124-100, registration RA82046, encountered turbulence during approach to land to Ted Stevens Anchorage International Airport (ANC), Anchorage, Alaska. The airplane was not damaged but two crew members received serious injuries. The flight was operating under the provisions of 14 CFR Part 129 as an unscheduled cargo flight from Campbell Army Airfield, Fort Campbell, Kentucky to ANC.

According to flight crew statements there were pilot reports of light turbulence in the area. While the airplane was about 40 miles from ANC at an altitude of about 13,000 feet and clear of clouds, the flight encountered severe turbulence that lasted for about 3 to 10 seconds. The flight crew reported that the airplane's g-meter recorded the event at -0.6 to +2.0 Gs.

At the time of the turbulence, one maintenance crew member was in the aft technical cabin returning from the lavatory and a second maintenance crewmember was in his seat with the seatbelt buckled but was jolted against the arm rest. Both crewmembers received serious injuries.