The pilot of the tailwheel-equipped airplane reported that during the landing roll, the airplane began to drift left. The pilot locked the left brake and the airplane exited the left side of the runway. The right wing struck the ground, causing the airplane to spin, and come to rest on its nose. The airplane sustained substantial damage to the horizontal stabilizer, right elevator, right wing and right aileron. The pilot reported there were no mechanical malfunctions or failures with the airplane prior to or during flight that would have precluded normal operation.