ENRTE TO DAYTON PASSING FLM ON THE BUCKE 3 ARR THE RPTR COMMENCED TRACKING THE ARR RATHER THAN THE 345 DEG RADIAL AMENDMENT THAT HAD BEEN ASSIGNED. ATC TURNED THE RPTR TO 300 DEGS TO 'INTERCEPT THE 345 DEG RADIAL AS FILED EXPECT VECTORS.' THEN THE FLC WENT THROUGH THE PUBLISHED 055 DEG RADIAL DURING A FREQ CHANGE. THE ATC TOLD THE FLC TO GO DIRECT TO DAYTON. THE RPTR HAD NOT EATEN FOR 9 HRS AND HAD SCHEDULED 48 STOPS ON THE 4 DAY TRIP WITH LONG DAYS AND MINIMUM REST ON THE OVERNIGHTS.

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ENRTE FROM CLT TO DAY UPON XING THE FALMOUTH VOR COMMENCED TO FLY THE BUCKE 3 ARR INTO DAY. THE RELEASE HAD THE FLM 345 DEG RADIAL TO INTERCEPT THE CVG 035 DEG RADIAL. THIS IS NOT WHAT IS NORMALLY DONE. CTLR CAUGHT ERROR AND WE WERE GIVEN A HDG TO REINTERCEPT THE FLM AT 345 DEG RADIAL. THEN WE WERE TOLD TO EXPECT VECTORS. THEN WE WERE CLRED AS FILED. ONCE ESTABLISHED ON THE 345 DEG RADIAL THIS WAS ALL OCCURRING SIMULTANEOUSLY WITH A FREQ CHANGE WE WENT THROUGH THE CVG 035 DEG RADIAL. THEN THE NEW CTLR CLRED US DIRECT TO DAY VOR. CONSISTENCY IN ROUTING AND ARRS WOULD HELP. I ALSO BELIEVE THAT THE FIRST CTLR; BY REESTABLISHING US ON THE FLM 345 DEG RADIAL SET US UP FOR THE SECOND DEV. A HDG OF 360 DEGS FOR THE CVG 055 DEG RADIAL WOULD HAVE WORKED BETTER. BY THE TIME WE WERE RE-ESTABLISHED ON THE FLM 345 DEG WE WERE VERY CLOSE TO THE CVG 055 DEG RADIAL. ALSO IT WAS NEARLY LUNCH TIME AND HAD ONLY A BANANA AND BAGEL TO EAT ALL DAY SINCE XA30 SHOW TIME THAT MORNING. THE LACK OF FOOD AS WELL AS LONG DUTY DAYS AND 6-8 LEGS PER DAY CAUSES FATIGUE WHICH IS A FACTOR IN SUCH OCCURRENCES.