A POTENTIAL CONFLICT ENSUES AT A NON TWR ARPT WHEN A C152 PVT PLT TAKES OFF ON RWY 21 WHICH WAS FAVORED BY THE WIND. A SENECA PA34 TAKES POS AT THE OTHER END; RWY 3. BOTH PLTS WERE SELF ANNOUNCING BUT THE PA34 CREW FAILED TO HEAR THE C152'S CALL.

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I WAS PREPARING TO DEPART ON A XCOUNTRY FLT FROM A NON TWRED ARPT. THE WINDSOCKS AND ASOS BROADCAST BOTH FAVORED RWY 21 (WIND 170 DEGS AT 7 KTS). (THIS RWY IS POSTED TO USE RWY 3 IN CALM OR XWIND CONDITIONS.) RWY IS 4200 FT LONG. 2 ACFT LANDED ON RWY 3 AS I DID MY RUN-UP. I WAS AT THE RUN-UP AREA AT THE N END OF RWY 3/21. (1 OF THOSE 2 LNDG ACFT WAS THE SENECA INVOLVED IN THIS.) WHEN I WAS READY TO TKOF; I TAXIED TO THE HOLD LINE AND VISUALLY SCANNED FOR TFC AND ALSO MONITORED RADIO CTAF/UNICOM. NO ONE WAS IN THE PATTERN AND THE SENECA WAS TAXIING SOUTHWARD; ON THE OPPOSITE SIDE OF THE RWY; ON THE TXWY. I ANNOUNCED BY RADIO THAT I WAS ENTERING THE 'PREFERRED RWY 21' AND BEGAN MY TKOF. AS I GOT CLOSE TO LIFT-OFF SPD; THE SENECA TAXIED INTO POS ON RWY 3;RIGHT IN MY PATH (BUT AT THE FAR END OF THE RWY). I CALLED 'SENECA; CESSNA IS TAKING OFF ON RWY 21' AND THE INSTRUCTOR CALLED BACK 'RWY 3 IS THE ACTIVE.' I SAID 'THIS IS A NON CTLED ARPT AND THE WINDS FAVOR RWY 21.' THE INSTRUCTOR CALLED BACK AND SAID 'YOU'RE GOING TO KILL SOMEBODY; WE'VE BEEN USING RWY 3 FOR 20 MINS.' AS I CALLED THE SENECA THE FIRST TIME; I HAD ALREADY DECIDED TO PROCEED WITH TKOF AS I WAS NEARLY AT FLYING SPD. I LIFTED OFF; BANKED/TURNED SLIGHTLY L (INTO THE WIND) AND FLEW A NORMAL DEP FROM THERE. I BELIEVE THE SENECA WAS CREWED BY A NON-NATIVE SPEAKER OF ENGLISH RECEIVING INSTRUCTION FROM A YOUNG CFI. THE SENECA DID ANNOUNCE IT WAS ENTERING RWY 3 -- BY THAT TIME I WAS ALREADY ROLLING DOWN RWY 21. ALL RADIO CALLS UP TO THAT POINT WERE IN A HEAVILY ACCENTED VOICE. AFTER I LIFTED OFF AND CALLED TO ALERT THE SENECA TO MY PRESENCE; ANOTHER VOICE (THE CFI; I PRESUME) TOOK OVER THE RADIO. I BELIEVE MY DECISION TO USE RWY 21 WAS CORRECT GIVEN THE WIND. I ALSO BELIEVE I ACTED PROPERLY IN VISUALLY CLRING THE AREA AND MAKING A SELF-ANNOUNCE RADIO CALL BEFORE ENTERING THE RWY. I BELIEVE THIS INCIDENT WAS CAUSED BY AN INATTENTIVE STUDENT (ADVANCED STUDENT MULTI-ENG) AND FLT INSTRUCTOR WHO DID NOT PAY ATTN TO MY RADIO CALL; DID NOT LOOK FOR TFC ON THE RWY BEFORE TAXIING INTO POS AND; DID NOT BOTHER TO CHK THE METEOROLOGICAL CONDITIONS; PREFERRING TO PRACTICE TKOFS AND LNDGS DOWNWIND; BECAUSE OTHER ACFT HAD BEEN DOING THE SAME THING. AFTER I MADE THE CALL TO TELL THE SENECA I WAS TAKING OFF; THE SENECA HELD ITS POS (INSTEAD OF PROCEEDING WITH THE TKOF). WE WERE NEVER VERY CLOSE TO EACH OTHER AND AT NO TIME DID I DOUBT MY ABILITY TO AVOID A COLLISION. I DO REGRET HAVING PARTICIPATED IN EVEN A BRIEF DEBATE OVER WHOSE MISTAKE IT WAS; OVER THE RADIO. BUT NOBODY USED PROFANITY.