DC9 FLC HAS RADIO FAILURE WHEN ATC IS CONFUSED ABOUT ROUTING.

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ACFT WAS RELEASED FROM YIP TO DELIVER CARGO TO ORF AND RETURN. AFTER ARR AT ORF; CLRNC WAS RECEIVED BACK TO YIP. AFTER CALLING OPS; THEY SAID WE MIGHT CHANGE DESTS. FO CALLED BACK TO CLRNC AND NOTIFIED HIM WE MIGHT HAVE A NEW DEST BUT WE WOULD NOT KNOW FOR AN HR; AND WHAT WOULD HE LIKE US TO DO. HE SAID HE WOULD MAKE OUR ESTIMATED TIME OF DEP LATER; AND IT WOULD BE GOOD FOR 2 HRS BEYOND THAT; AND HE'D WATCH FOR A NEW FLT PLAN. OUR DEST DID CHANGE; AND WE RECEIVED CLRNC TO ROA. CLRNC WAS TO ROA VIA THE NORFOLK 3 DEP; RADAR VECTORS; WAIKS; THE ORF 290 DEG RADIAL TO 79 DME; LYH; THEN DIRECT 4000 FT. I DON'T RECALL ANY MENTION OF THE PREVIOUS CLRNC BY ATC OR THE CREW. WE DEPARTED AND A SHORT TIME LATER; DEP CTL CHANGED OUR SQUAWK. WE DIDN'T REALIZE THIS WAS THE CODE GIVEN EARLIER FOR YIP. WE WERE LEVEL IN CRUISE AT FL240 APPROX 30 MI FROM LYH WHEN I REALIZED WE HAD LOST OUR #2 COM (THE ONE WE NORMALLY USE) AND SWITCHED TO #1 COM. UPON CHKING BACK IN WITH ZDC; THE CTLR STATED SHE HAD TRIED TO REACH US SEVERAL TIMES AND TO SAY OUR HDG AND INTENTIONS. I REPLIED OUR #2 COM HAD FAILED; WE WERE HDG ON COURSE TO LYH; AND WE INTENDED TO LAND AT ROA. WE WERE ASSIGNED A NEW FREQ AND UPON CHK-IN; WERE ASKED THE SAME QUESTIONS. THE CTLR ALSO ASKED ABOUT OUR CLRNC AND WHERE WE HAD RECEIVED IT; AND TO CALL THEM AFTER LNDG. WHEN I CALLED; I WAS TOLD TFC HAD BEEN RERTED AROUND US BECAUSE THEY EXPECTED US TO TURN NBOUND AFTER THE 70 DME FIX; NOT WBOUND. IT WAS AFTER THIS CALL I REALIZED THE SQUAWK ISSUED BY DEP WAS FROM THE YIP CLRNC. THAT CLRNC HAD TAKEN NBOUND TO FAK AFTER THE 79 DME FIX OUT OF ORF. UNFORTUNATELY; OUR RADIO FAILED AT THE MOST INOPPORTUNE TIME SOMEWHERE BY THAT FIX. I HAD MENTIONED EARLIER IN THE DAY TO MY FO HOW SQUAWK CHANGES MADE ME NERVOUS BECAUSE IT MADE ME FEEL I HAD DONE SOMETHING WRONG. FROM NOW ON; I'LL KEEP IN MIND HOW MUCH INFO IS PASSED ALONG WITH THAT CODE. THE PREVIOUS CLRNC TO YIP SHOULD HAVE BEEN CANCELED ALTOGETHER -- A PRACTICE WE NORMALLY FOLLOW.