MEM LCL CTLR ISSUES A TKOF CLRNC WITH ANOTHER ACFT IN EXCLUSION AREA.

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I WAS WORKING THE LCL CTL #2 POS THIS MORNING DURING THE INBOUND PUSH. MEM WAS IN A N CONFIGN; LNDG RWYS 36L; 36R; AND 27; DEPARTING RWYS 36C; AND 27. GND CTL #2 WAS TAXIING A C550 FROM FBO TO RWY 36C FOR DEP '...VIA TXWY A; HOLD SHORT OF TXWY S.' THIS RESTR IS TO PROTECT THE PATH OF ANY ACFT DEPARTING RWY 36C; AS TXWY A CROSSES THE DEP END OF RWY 36C. LCL PROCS MANDATE THAT NO VEHICLES OR ACFT BE ALLOWED ON TXWY A BTWN TXWYS S AND C WHEN ACFT ARE DEPARTING RWY 36C. I CLRED THE CRJ2 FOR TKOF FROM RWY 36C. AS THE CRJ2 WAS ROTATING; I NOTICED THE C550 WAS XING TXWY S AND PENETRATING THE PROTECTED AREA OF TXWY A; XING JUST UNDER THE CRJ2. GND CTL #2 NOTICED THIS AT THE SAME INSTANT; BUT IT WAS TOO LATE TO STOP THE C550; AND THE CRJ2 WAS AIRBORNE. THE C550 SAID THAT HE HAD BEEN INSTRUCTED TO HOLD SHORT OF TXWY C. THIS HAPPENS VERY OFTEN AT MEM; AND COULD PROVE FATAL IF THE WRONG ACFT WERE EVER INVOLVED. FOR INSTANCE: HVY JETS OFTEN REQUIRE RWY 36C FOR DEP DUE TO WT AND OPERATIONAL CHARACTERISTICS. THESE HVY JETS WILL OFTEN UTILIZE NEARLY EVERY INCH OF THE RWY FOR THEIR DEP ROLL. IF AN ACFT WERE TO TAXI THROUGH THIS PROTECTED AREA VIA TXWY A; IT IS QUITE POSSIBLE THAT THE RWY 36C DEPARTING TFC WOULD IMPACT THE TAXIING TFC ON TXWY A. THIS WOULD BE EVEN MORE CRITICAL IF THE TXWY A TFC WERE ANY ACFT THAT HAD A TALL TAIL. IN THE FUTURE; I WILL INCLUDE TXWY A AS PART OF MY DEP SCAN BEFORE CLRING ANY ACFT FOR TKOF FROM RWY 36C. IF I OBSERVE ANY TFC ON TXWY A; I WILL CONFIRM WITH GND CTL #1 THAT THE TFC IS HOLDING FOR MY DEP TFC. IF A HVY IS INVOLVED; OR IF THE TXWY A TFC IS AN ACFT THAT HAS A TALL TAIL; THEN I WILL WAIT UNTIL I OBSERVE THE TFC COME TO A COMPLETE STOP. ADDITIONALLY; BETTER COORD OR CONFIRMATION MIGHT BE HELPFUL FROM GND CTL #1 TO ENSURE THAT TFC DOES NOT PENETRATE THIS SAFETY AREA.