49 fatalities

Aircraft Deviates from Assigned Runway During Takeoff at Blue Grass Airport (N431CA)

Lexington-Blue Grass, United States of AmericaTakeoff (climb)

On August 27, 2006, a Canadair RegionalJet CRJ-200 (registration N431CA) operated by Comair (Delta Connection) was involved in an aviation accident near Lexington-Blue Grass, United States of America during takeoff. 49 people were killed. Investigators recorded the probable cause as: The flight crew members' failure to use available cues and aids to identify the airplane's location on the airport surface during taxi and their failure to cross-check and verify that the airplane was on the correct runway before takeoff. This summary draws on records from the Bureau of Aircraft Accidents Archives (B3A); 8 related events involving the same aircraft type or operator are linked below.

Sourcesthe Bureau of Aircraft Accidents Archives (B3A)Primary report: the U.S. National Transportation Safety Board (NTSB) Aircraft Accident ReportsUpdated 2026-07-04Data APIEditorial standards

A Part 121 flight crashed during takeoff from Blue Grass Airport after lining up on the wrong runway. The captain, flight attendant, and 47 passengers were killed; the first officer was seriously injured.

Accident Overview

On a night with visual meteorological conditions, a commercial aircraft operating under 14 Code of Federal Regulations Part 121 crashed during takeoff from Blue Grass Airport in Lexington, Kentucky. The flight was en route to Hartsfield-Jackson Atlanta International Airport in Atlanta, Georgia. The aircraft was destroyed by impact forces and a subsequent post-crash fire.

Sequence of Events

The flight crew received instructions to take off from runway 22. However, during the takeoff roll, the crew inadvertently lined up the aircraft on runway 26 instead. The aircraft ran off the end of the runway and struck the airport perimeter fence, trees, and terrain. The captain, flight attendant, and 47 passengers were killed; the first officer sustained serious injuries.

Probable Cause

The official investigation determined the probable cause to be the flight crew members' failure to use available cues and aids to identify the airplane's location on the airport surface during taxi and their failure to cross-check and verify that the airplane was on the correct runway before takeoff. Contributing to the accident were the flight crew's nonpertinent conversation during taxi, which resulted in a loss of positional awareness, and the Federal Aviation Administration's failure to require that all runway crossings be authorized only by specific air traffic control clearances.

Frequently asked questions

What happened in the 27 Aug 2006 Canadair RegionalJet CRJ-200 accident near Lexington-Blue Grass, United States of America?

A Part 121 flight crashed during takeoff from Blue Grass Airport after lining up on the wrong runway. The captain, flight attendant, and 47 passengers were killed; the first officer was seriously injured.

Were there any fatalities in the 27 Aug 2006 Canadair RegionalJet CRJ-200 accident?

The accident was fatal, resulting in 49 fatalities.

What aircraft was involved and where did it happen?

The accident on 27 Aug 2006 involved a Canadair RegionalJet CRJ-200, registration N431CA, operated by Comair (Delta Connection), at Lexington-Blue Grass, United States of America.

What was the probable cause of the accident?

The flight crew members' failure to use available cues and aids to identify the airplane's location on the airport surface during taxi and their failure to cross-check and verify that the airplane was on the correct runway before takeoff. Contributing to the accident were the flight crew's nonpertinent conversation…